Luxor is a safe city for travelers. I have guided clients from across the world — including solo women, families with young children, and elderly visitors — without a single serious safety incident in seventeen years of work. That said, a few practical things are worth knowing.
The primary health concern in summer is heat. It is not dramatic if you manage it: early starts, shade, water, and pacing. I have seen determined travelers push through midday heat and pay for it with a day in bed. I will not let that happen to my clients if I can help it — I monitor how people are doing and adjust the plan.
Food and water: drink bottled water, including when brushing teeth in the first days if you have a sensitive stomach. Cooked street food from busy stalls is generally safe. Fresh salads and unpeeled fruit from unlicensed vendors carry more risk. I can recommend restaurants I trust.
Travel insurance: I strongly recommend it. Not because Luxor is dangerous, but because medical evacuation from Egypt is expensive without it, and unexpected events — a sprained ankle on uneven terrain, a stomach illness, a delayed flight — are covered for a modest annual premium. Get the policy before you travel, not after you land.